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This volume presents the official proceedings of the National Day of Applied Microbiology in the Service of Industry (JNMASI’25), held on May 8th, 2025 at M’Hamed Bougara University of Boumerdes. The publication brings together a rich body of work highlighting the essential roles of microorganisms across major industrial, agricultural, environmental, and medical sectors. Throughout this scientific day, researchers explored the contributions of fermentation and microbial processes to the food and chemical industries, where yeasts and bacteria enable the production of ethanol, biofuels, fermented dairy products, probiotics, enzymes, amino acids, and other fundamental biomolecules. The discussions also addressed agricultural challenges resulting from excessive use of fertilizers and pesticides, emphasizing sustainable alternatives such as biofertilizers, biopesticides, and organic farming to preserve soil fertility and environmental balance. Environmental microbiology featured prominently, showcasing the vital role of microorganisms in nutrient recycling, pollutant degradation, ecosystem management, and biodiversity preservation. In the medical field, the event highlighted the significant contribution of industrial microbiology to the development of new therapeutic molecules, including antibiotics, vitamins, natural precursors, and steroid drugs derived from microbial synthesis. The proceedings further examined the integration of biosafety, risk modelling, and artificial intelligence, demonstrating how AI-driven tools can anticipate, assess, and manage microbiological risks in public health, agriculture, and the food industry. Under the slogan “Innovate, Transform, Produce: The Power of Applied Microbiology for Industry,” this publication offers a comprehensive scientific overview aimed at researchers, students, and professionals interested in the innovative microbial solutions shaping the future of agro-ecological transition, environmental protection, and national food and energy security.

Proceedings of the 2nd International Conference on Bioinformatics (2ICB’24) presents a comprehensive scientific record of the research contributions showcased during the second edition of the International Conference on Bioinformatics, held at M’Hamed Bougara University of Boumerdes (UMBB), Algeria, on November 13–14, 2024. This volume compiles an extensive collection of keynote lectures, invited talks, oral communications, and poster abstracts that highlight the latest advancements in bioinformatics and OMICS sciences, including genomics, proteomics, metabolomics, transcriptomics, multi-omics integration, and structural bioinformatics.
The proceedings reflect the dynamic scientific dialogue among internationally recognized researchers, experts, and early-career scientists, addressing contemporary issues such as high-throughput genetic analysis, computational modeling, biomarker discovery, machine learning applications in health sciences, drug design, microbial genomics, and the development of innovative bioinformatics tools. By bringing together contributions from leading universities, research institutes, and specialized laboratories worldwide, this book illustrates the importance of interdisciplinary collaboration in tackling complex biological and medical challenges. Rich in theoretical foundations and practical applications, the volume serves as a valuable reference for researchers, students, and professionals seeking to deepen their understanding of data-driven biological research and to keep pace with emerging methodologies shaping the future of bioinformatics and biomedical science.

In a world where exile collides with memory, and humans intersect with animals, The Republic of the Dog unfolds as a profound meditation on power, alienation, and identity. Through the ambiguous relationship between an Eastern refugee in Europe and a dog that seems to understand the new order better than people do, the novel exposes the hidden logic of modern societies.

Dogs in this novel are not marginal creatures; they are mirrors reflecting the contradictions of contemporary life—obedience and rebellion, affection and fear, freedom and surveillance. With a reflective narrative voice infused with philosophy, history, and cultural memory, the author raises unsettling questions about belonging, humanity, and who truly holds sovereignty in a world where values are constantly being redefined.

The Republic of the Dog is not a story about a dog—it is a story about a human being who becomes a stranger within a republic that does not resemble him, only to realize that alienation is not defined by geography, but by one’s position within the system.
A bold, ironic, and deeply human novel that reveals the fragility of power when viewed from ground level… where dogs stand.

Synopsis – Roses Behind Bars

Roses Behind Bars is a powerful prison novel by Mohamed Ezzedine Gharred (Jemaiel) that unveils the harrowing experiences of Tunisian female political prisoners under the authoritarian regime of President Ben Ali. Through a documentary-style narrative, the novel fuses history and fiction to portray the tragic yet heroic journey of women detainees who endured unspeakable torture, humiliation, and violence in the dark cells of the Ministry of Interior, interrogation centers, and women’s prisons such as Mneehla and Manouba.

Narrated primarily through the voice of Salwa Bjawi, the novel pays tribute to iconic resistance figures such as Mahreziya Bel-Abed, Salwa Al-Aswad, and Amina Al-Amiri, who suffered brutal repression for their political activism and affiliation with the Ennahdha movement. Drawing inspiration from the legendary pre-Islamic poetess al-Khansāʾ, the title alludes to the dignity, resilience, and unbreakable spirit of these women — roses blooming behind prison bars.

The story blends personal memories, historical testimonies, and collective trauma to shed light on systemic abuse, particularly sexual violence used as a tool of oppression. It also confronts the reader with ethical and existential questions about honor, identity, state brutality, and the lingering psychological scars borne by survivors.

At once a literary protest and a historical witness, Roses Behind Bars transcends conventional storytelling by dismantling taboos and restoring the voices of those silenced. It is not merely a tale of suffering, but also of moral resistance, intergenerational struggle, and the undying hope for justice.

In the heart of a snow-covered forest on the outskirts of Paris, wealthy Canadian businessman Robert Densen retreats to his secluded cabin with his elegant wife, Eva, seeking peace. But on the eve of his fifty-fifth birthday, a brutal assassination shatters the stillness.

Enter Inspector Nurhan Yazdji—a sharp-minded detective with a relentless drive for justice. As she unravels the layers of a chilling murder, she uncovers far more than a simple crime: a web of buried family secrets, personal betrayals, and a cold, calculated killer who always stays one step ahead.

From luxury estates to the shadowy corners of a decaying Paris, Season of Terror is a masterfully written thriller that blends psychological tension with social commentary. With vivid prose and cinematic pacing, it explores the shifting boundaries between guilt and innocence, faith and skepticism, justice and vengeance.

Gripping, elegant, and deeply human—this is not just a crime novel. It’s a descent into the darkest corners of modern life.

The Gut–Brain Axis: Gut Microbiota and Emotional Regulation, by Dr. Mounira Ariech, explores the complex relationship between the digestive system, nutrition, brain function, and emotional well-being. It presents the gut microbiota as an active biological system that communicates continuously with the brain and contributes to the regulation of stress, anxiety, mood, and behavior.

The book begins by explaining the physiological and psychological foundations of stress and anxiety and examining how diet affects neurotransmitter production, inflammation, the immune system, and the hypothalamic–pituitary–adrenal axis. It then analyzes the microbiota–gut–brain axis as a bidirectional communication network involving neural, endocrine, immunological, and metabolic pathways. Particular attention is given to the vagus nerve, serotonin, GABA, short-chain fatty acids, the kynurenine pathway, and neurotrophic factors involved in emotional regulation.

The book also discusses how omega-3 fatty acids, magnesium, B vitamins, vitamin D, antioxidants, fiber, fermented foods, and other beneficial nutrients may support microbial diversity and psychological resilience. In contrast, diets rich in refined sugars, trans fats, excess sodium, chemical additives, and ultra-processed foods may contribute to intestinal dysbiosis, inflammation, anxiety, and emotional instability.

Ultimately, the book advocates an integrated approach combining nutritional care with psychological support. It presents targeted dietary strategies and microbiome-focused interventions as accessible complementary tools for managing anxiety, reducing the effects of chronic stress, and promoting long-term emotional stability.